Searchable abstracts of presentations at key conferences in endocrinology

ea0016p291 | Endocrine tumours | ECE2008

Differences in the gene expression patterns of several immune related genes in various human adrenocortical tumors

Szabo Peter , Wiener Zoltan , Tombol Zsofia , Tolgyesi Gergely , Kovesdi Katalin , Farkas Roland , Horanyi Janos , Gaillard Rolf C , Falus Andras , Racz Karoly , Igaz Peter

Introduction: The adrenal cortex is highly involved at the immune-neuroendocrine interface, and several cytokines are known to influence the proliferation, differentiation, apoptosis and hormone production of adrenocortical cells. We therefore hypothesized that immune mediators might be involved in adrenal tumorigenesis, as well. Gene expression patterns of various inflammatory and immune mediators were studied by a functional genomics/bioinformatics approach.<p class="abs...